Director: Prof. Rajeev S. Menon

Associated faculty members

1. Dr. Suja T. D.
2. Prof. D. Bahulayan
3. Dr. Derry Holaday M. G. 

Fundamental questions about life and living systems invariably takes the investigator to the realms of organic and biomolecular chemistry. Advanced research in these areas not only enhances of our understanding of life, but also enables us to intervene and improve the conditions of living beings. The applications are numerous in areas such as diagnosis (assays, biosensors), prevention (vaccines, gene editing), modification (genetic engineering), therapy (pharmaceuticals), implants (biocompatible materials), supplements (agrochemicals) and sustainable development (biocatalysis, biomass valorisation). The Organic and Biomolecular Research Centre (OBCRC) will plan, co-ordinate and implement research activities aimed at the design, synthesis, development and fine-tuning of properties of novel molecules suitable for each of the above-mentioned purposes. A few representative publications that constitute the foundation of the intended activities of the centre are given below.

Related Publications:

1. S. Shankar and D. Bahulayan, Chemistry, Chemical Biology and Photophysics of Certain New Chromene-Triazole-Coumarin Triads as Fluorescent Inhibitors of CDK2 and CDK4 Induced Cancers, New Journal of Chemistry, 2019, 43, 13863-13872.
2. S.S.E. Puthumana and D. Bahulayan, ICT-Based Blue-Emitting Dual-Functional Probe (Ugi EML BLUE) for Bio-Imaging and Cytotoxic Activities on HeLa Cells, ChemistrySelect, 2019, 4, 5366-5374.
3. Effective utilization of quartz crystal microbalance as a tool for biosensing applications P.J. Jandas, K. Prabakaran, Jingting Luo, Derry Holaday M G, Sensors and Actuators A: Physical 2021, 331, 113020.
4. Ti₃C₂Tx MXene-Au nanoparticles doped polyimide thin film as a transducing bioreceptor for real-time acoustic detection of carcinoembryonic antigen P. J. Jandas, K. Prabakaran, Jingting Luo, Chen Fu Yong Qing Fu, Derry Holaday M. G. Sensors and Actuators A: Physical 2021, 331, 112998.
5. Copper-catalyzed three-component synthesis of aminonaphthoquinonesulfonylamidine conjugates and in-vitro evaluation of their antiproliferative activity. Suja T. D.; Divya, K. V. L.;Naik, L. V.; A. R Kumar, A. R.; Kamal, A. Bioorg. Med Chem Lett, 2016, 26, 2072.
6. A facile atom-economical synthesis of highly substituted pyrazolo-N-methyl-piperidine grafted spiro-indenoquinoxaline pyrrolidine heterocycles via a sequential multicomponent reaction. Gavaskar, D, and Suresh Babu A. R. Synth. Commun.2020, 50, 3820.